2017
Authors
Martin J Connolly; Ngaire Kerse; Tim Wilkinson; Oliver Menzies; Anna Rolleston; Yih Harng Chong; Joanna B Broad; Simon A Moyes; Santosh Jatrana; Ruth Teh
Abstract
Serum testosterone (T) levels in men decline with age. Low T levels are associated with sarcopenia and frailty in men aged >80 years. T levels have not previously been directly associated with disability in older men. We explored associations between T levels, frailty and disability in a cohort of octogenarian men.
Data was used from all men from Life and Living in Advanced Age Cohort Study in New Zealand, a longitudinal cohort study in community-dwelling older adults.
In conclusion - men over 80 years, we confirm an association between T levels and baseline frailty scores. The new finding of association between T levels and disability is potentially relevant to debates on T supplementation in older men, though, as associations were not present at 24 months, further work is needed.
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