Does potentially inappropriate prescribing predict an increased risk of admission to hospital and mortality? A longitudinal study of the ‘oldest old’

2020


Authors

Karen Cardwell, Ngaire Kerse, Carmel M. Hughes, Ruth Teh, Simon A. Moyes, Oliver Menzies, Anna Rolleston, Joanna B. Broad & Cristín Ryan



Abstract

Potentially inappropriate prescribing (PIP) is associated with negative health outcomes, including hospitalisation and mortality. Life and Living in Advanced Age: a Cohort Study in New Zealand (LiLACS NZ) is a longitudinal study of Māori (the indigenous population of New Zealand) and non-Māori octogenarians. Health disparities between indigenous and non-indigenous populations are prevalent internationally and engagement of indigenous populations in health research is necessary to understand and address these disparities.


Using LiLACS NZ data, this study reports the association of PIP with hospitalisations and mortality prospectively over 36-months follow-up. PIP was associated with an increased risk of hospitalisation and mortality in this cohort.

Omissions appear more important for Māori in predicting hospitalisations, and PIMs were more important in non-Māori in predicting mortality.


These results suggest understanding prescribing outcomes across and between population groups is needed and emphasises prescribing quality assessment is useful.





Publication Link

https://doi.org/10.1186/s12877-020-1432-4